adaptIVPT adaptTest adestr adpss asd ASSISTant BAR BayesCTDesign BayesianMCPMod bcrm BDP2 BinGSD blockrand BOIN brada carat CARM cats clinfun clinsig CohortPlat coin conf.design cosa covadap ctrdata dfcrm dfmta DTAT epibasix esDesign eselect ewoc experiment FrF2 glmmTMB gMCP grouprar grpseq gscounts GSED gsMAMS gsrsb HH iAdapt ldbounds lme4 logistf longpower lrstat MABOUST MAMS maxcombo MCPMod meta metafor metaLik metasens MinEDfind monitOS multcomp netmeta nlme nphRCT nppbib OncoBayes2 PK pmvalsampsize pocrm PowerTOST PowerUpR pwr PwrGSD RABR randomizeR RARfreq RBesT remiod replicateBE rmeta rpsftm SAME samplesize SEARS seqmon simglm speff2trial ssanv SurrogateSeq TEQR ThreeGroups tLagInterim TrialSize UnifiedDoseFinding